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| Address: |
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Colorado State University
Department of
Biochemistry and Molecular Biology
MRB 316
Fort
Collins, CO 80523-1870
USA
Phone:
+970.491.5586
Fax:+970.491.0494
E-mail:
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| Education: |
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2003 |
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PhD, Biochemistry and Molecular Biology,
Colorado State University - Thesis: Histone binding
preference and oligomerization of the nucleosome
assembly protein 1 (NAP1)
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| 1999 |
Master of Science, Biochemistry and
Molecular Biology, Colorado State
University |
| 1990 |
Bachelor of Arts, Environmental,
Population and Organismic
Biology |
| Research
Experience: |
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2003 -
present |
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Post Doctoral
Fellow, Advisor: Dr. Jeffrey Hansen, Department of
Biochemistry and Molecular Biology, Colorado State
University, Fort Collins, CO |
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1998 -
2003 |
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Graduate Research
Student, Advisor: Dr. Karolin Luger Department of
Biochemistry and Molecular Biology, Colorado State
University, Fort Collins, CO
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1992 -
1998 |
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Lab Technician, Dr.
Joel M. Gottesfeld, The Scripps Research Institute,
Medical Biology Institute, La Jolla, CA |
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1991 -
1992 |
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Lab Technician, Dr.
Ann J. Feeney, Medical Biology Institute, La Jolla,
CA |
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| Publications: |
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Park
Y.J., Chodaparambil J.V., Bao Y., McBryant S.J., Luger
K. (2004) Nucleosome assembly protein 1 exchanges
histone H2A-H2B dimers and assists nucleosome
sliding.
J Biol Chem. 2005 Jan
21;280(3):1817-25.
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McBryant, S.J., and Peersen, O.B. (2004)
Self-association of the yeast nucleosome assembly
protein 1. Biochemistry, 43, 10592-10599.
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McBryant, S.J., Abernathy, S.M., Laybourn, P.J.,
Nyborg, J.K., and Luger, K. (2003) Preferential binding
of the histone (H3-H4)2 tetramer by NAP1 is mediated by
the amino- terminal histone tails. J Biol Chem,
278, 44574-44583
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Vendel, A.C., McBryant, S.J., and Lumb, K.J.
(2003) KIX-Mediated assembly of the CREB-CBP-HTLV-1 Tax
complex. Biochemistry, 42, 12481-12487.
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Livengood, J.A., Scoggin, K.E., Van Orden, K.,
McBryant, S.J., Edayathumangalam, R.S., Laybourn, P.J.
and Nyborg, J.K. (2002) p53 Transcriptional activity is
mediated through the SRC1-interacting domain of
CBP/p300. J Biol Chem, 277, 9054-9061.
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McBryant, S.J., Baird, E.E., Trauger, J.W.,
Dervan, P.B. and Gottesfeld, J.M. (1999) Minor groove
DNA-protein contacts upstream of a tRNA gene detected
with a synthetic DNA binding ligand. J Mol Biol,
286, 973-981.
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McBryant, S.J. and Gottesfeld, J.M. (1997)
Differential kinetics of transcription complex assembly
distinguish oocyte and somatic 5S RNA genes of Xenopus.
Gene Expr, 6, 387-399.
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McBryant, S.J., Gedulin, B., Clemens, K.R.,
Wright, P.E. and Gottesfeld, J.M. (1996) Assessment of
major and minor groove DNA interactions by the zinc
fingers of Xenopus transcription factor IIIA. Nucleic
Acids Res, 24, 2567-2574.
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McBryant, S.J., Meier, E., Leresche, A., Sharp,
S.J., Wolf, V.J. and Gottesfeld, J.M. (1996) TATA-box
DNA binding activity and subunit composition for RNA
polymerase III transcription factor IIIB from Xenopus
laevis. Mol Cell Biol, 16, 4639-4647.
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McBryant, S.J., Kassavetis, G.A. and Gottesfeld,
J.M. (1995) Repression of vertebrate RNA polymerase III
transcription by DNA binding proteins located upstream
from the transcription start site. J Mol Biol,
250, 315-326.
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McBryant, S.J., Veldhoen, N., Gedulin, B.,
Leresche, A., Foster, M.P., Wright, P.E., Romaniuk, P.J.
and Gottesfeld, J.M. (1995) Interaction of the RNA
binding fingers of Xenopus transcription factor IIIA
with specific regions of 5 S ribosomal RNA. J Mol
Biol, 248, 44-57.
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Clemens, K.R., Zhang, P., Liao, X., McBryant,
S.J., Wright, P.E. and Gottesfeld, J.M. (1994) Relative
contributions of the zinc fingers of transcription
factor IIIA to the energetics of DNA binding. J Mol
Biol, 244, 23-35.
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Clemens, K.R., Wolf, V., McBryant, S.J., Zhang,
P., Liao, X., Wright, P.E. and Gottesfeld, J.M. (1993)
Molecular basis for specific recognition of both RNA and
DNA by a zinc finger protein. Science, 260,
530-3.
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