Hansen, J.C. and
Wolffe, A.P. (1992) Influence of Chromatin Folding on Transcription
Initiation and Elongation by RNA Polymerase III. Biochemistry 31,
7977-7988.
Hansen, J.C. and Lohr, D. (1993) Assembly and Structural Properties of
Subsaturated Chromatin Arrays. J. Biol. Chem. 268, 5840-5848.
Fletcher, T. M., Krishnan, U., Serwer, P. and Hansen, J.C. (1994)
Quantitative Agarose Gel Electrophoresis of Chromatin: Nucleosome-Dependent
Changes in Charge, Shape And Flexibility at Low Ionic Strength. Biochemistry
33, 2226-2233.
Schwarz, P. M. and Hansen, J.C. (1994) Formation and Stability of Higher
Order Chromatin Structures. Contribution of the Histone Octamer. J.
Biol. Chem. 269, 16284-16289.
Hansen, J. C. and Wolffe, A. P. (1994) A Role for Histones H2A/H2B in
Chromatin Folding and Transcriptional Repression. Proc. Natl. Acad. Sci.
91, 2339-2343.
Fletcher, T. M., Serwer, P. and Hansen, J.C. (1994) Quantitative
Analysis of Macromolecular Conformational Changes Using Agarose Gel
Electrophoresis of Chromatin: Application to Chromatin Folding. Biochemistry
33, 10859-10863.
Fletcher, T.M. and Hansen, J.C. (1995) Core Histone Tail Domains Mediate
Oligonucleosome Folding and Nucleosomal DNA Organization Through
Distinct Molecular Mechanisms. J. Biol. Chem. 270, 25359-25362.
Schwarz, P.M., Felthauser, A., Fletcher, T.M. and Hansen, J.C. (1996)
Reversible Oligonucleosome Self-Association: Dependence on Divalent
Cations and Core Histone Tail Domains. Biochemistry 35, 4009-4015.
Tse, C. and Hansen, J.C. (1997) Hybrid Trypsinized Nucleosomal Arrays:
Identification of Multiple Functional Roles of the H2A/H2B and H3/H4
N-termini in Chromatin Fiber Compaction. Biochemistry 36, 11381-11388.
Tse, C., Sera, T., Wolffe, A.W., and Hansen, J.C. (1998) Acetylation-induced
Decondensation of Nucleosomal Arrays Dramatically Facilitates
Transcription by RNA Polymerase III. Mol. Cell. Biol. 18, 4629-4638.
Tse, C., Fletcher, T. M., and Hansen, J.C. (1998) Enhanced Transcription
Factor Access to Arrays of H3/H4 Tetramer-DNA Complexes: Implications
for Replication and Transcription. Proc. Natl. Acad. Sci. 95,
12169-12173.
Carruthers, L.M.., Bednar, J., Woodcock, C. and Hansen, J.C. (1998)
Linker Histones Stabilize the Intrinsic Salt-dependent Folding of
Nucleosomal Arrays: Mechanistic Ramifications for Higher Order Chromatin
Folding. Biochemistry, 37, 14776-14787.
Bednar, J., Horowitz, R.A., Grigoryev, S.A., Carruthers, L.C., Hansen,
J.C., Koster, A.J., and Woodcock, C. L. (1998) Nucleosomes, Linker DNA
and Linker Histone Form a Unique Structural Motif that Directs the
Higher Order Folding and Compaction of Nucleosomal Arrays. Proc. Natl.
Acad. Sci. 95, 14173-14178.
Tse, C., Ruiz-Garcia, A.B, Georgieva, E.I., Sendra, R., and Hansen, J.C.
(1998) Gcn5p, a Transcription-Related Histone Acetyltransferase,
Acetylates Nucleosomes and Folded Nucleosomal Arrays in the Absence of
Other Protein Subunits. J. Biol. Chem. 273, 32388-32392.
Logie, C., Tse, C., Hansen, J.C., and Peterson, C.L. (1999) The Core
Histone N-terminal Domains are Required for Multiple Rounds of Catalytic
Remodeling by the SWI/SNF and RSC Complexes. Biochemistry 38, 2514-2522.
Pollard, K., Samuels, M.L., Crowley, K.A., Hansen, J.C., and Peterson,
C.P. (1999) Functional Interaction Between GCN5 and Polyamines: a New
Role for Core Histone Acetylation. EMBO J. 18, 5622-5633.
Sendra, R., Tse, C., and Hansen, J.C. (2000) The Yeast Histone
Acetyltransferase A2 Complex, but not free Gcn5p, Binds Stably to
Nucleosomal Arrays. J. Biol. Chem. 275, 24928-24934.
Carruthers, L.M. and Hansen, J.C. (2000) The Core Histone N-termini
Function Independently of Linker Histones During Chromatin Condensation
J. Biol. Chem. 275, 37285-37290.
Georgel, P.T., Palacios DeBeer, M.A., Pietz, G., Fox, C.A. and Hansen,
J.C. (2001) Sir3-dependent Assembly of Supramolecular Chromatin
Structures in vitro. Proc. Natl. Acad. Sci., 98, 8584-8589.
Horn P.J., Crowley KA, Carruthers LM, Hansen JC, Peterson CL (2002) The
SIN Domain of the Histone Octamer is Essential for Intramolecular
Folding of Nucleosomal Arrays. Nature Str. Biol. 9, 167-171.
Fan, J., Gordon F, Luger K, Hansen JC, Tremethick DJ (2002) The
Essential Histone Variant H2A.Z Regulates the Equilibrium Between
Different Chromatin Conformational States Nature Str. Biol. 9, 172-176.
Horn PJ, Carruthers LM, Logie C, Hill DA, Solomon MJ, Wade PA, Imbalzano
AN, Hansen JC, Peterson CL (2002) Phosphorylation of Linker Histones
Regulates ATP-dependent Chromatin Remodeling Enzymes. Nature Str. Biol.
9, 263-267.
Georgel, P.T., Horowitz- Scherer, R.A., Adkins, N., Woodcock, C.L.,
Wade, P.W. and Hansen, J.C. (2003) Chromatin Compaction by Human MeCP2:
Assembly of Novel Secondary Chromatin Structures in the Absence of DNA
Methylation. J. Biol. Chem., 278, 32181-32188.
Georgel, P.T., Fletcher, T.M., Hager G., and Hansen, J.C. (2003)
Formation of Condensed Secondary and Tertiary Chromatin Structures by
Genomic MMTV Promoters. Genes Dev., 17, 1617-1629.
Lu, X. and Hansen, J.C. (2004) Identification of Specific Functional
Sub-domains Within the Linker Histone H1º C-terminal Domain. J. Biol.
Chem. 279, 8701-07. Epub ahead of print: 2003 Dec 10.
P. Widlak, M. Kalinowska, M.H. Parseghian,
X. Lu, J.C. Hansen, and W.T. Garrard (2005) Histone H1 Stimulates DNA
Cleavage by the Apoptotic Nuclease, DNA Fragmentation Factor
(DFF40/CAD), Through its Basic C-Terminal Domain. Biochemistry
44, 7871-78.
Gordon, F., Luger, K.,
and Hansen, J.C. (2005) The Core Histone N-Terminal Tail Domains
Function Independently and Additively During Salt-Dependent
Oligomerization of Nucleosomal Arrays. J. Biol. Chem. In press.
Epub ahead of print: Jul 19, 2005
Zheng, C., Lu, X.
Hansen, J.C. and Hayes, J.J. (2005) Salt-dependent Intra- and Inter-Nucleosomal
Interactions of the H3 Tail Domain in a Model Oligonucleosomal Array.
J. Biol. Chem. Epub ahead of print: Aug 2
